In this paper,the mesoporous silica were prepared under hydrothermal conditions by employing polyethylene glycol 6000 and β-Cyclodextrins(CD) as compound templates.The effects of hydrothermal temperature and hydrothermal time of the pore structure、pore distributing and surface area of the mesoporous silica were discussed.The mesoporous silica were determined by FT-IR、N2 adsorption-desorption isotherms and transmission electron microscopy(TEM).Under the conditions of hydrothermal temperature 100℃、hydrothermal time 6h and calcining at 450℃ for 4h,the experimental results indicate that the mesoporous silica have better dispersed property、uniform pore and particle diameter and high surface area.The formed mesoporous silica have the ability of adsorbing phenol from waste water.